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B12 Deficiency and Cognitive Dysfunction

This study showed that vitamin B12 deficiency causes reversible cognitive problems. Could the B12 deficiency be causing the Alzheimer's? If yes, then it's another reversible cause.

In this study, they used cases of very severely low B12 levels. Other studies show that evidence of brain problems from B12 deficiency are seen even at B12 levels of 300, and likely even higher (anything under 209 is sadly still considered normal by some physicians). Biochemical signs of B12 deficiency are seen even at B12 levels over 540.

In a study involving 36 patients between the ages of 16 and 80 years of age (32 patients being over the age of 40 years) with low serum B12 or megaloblastic bone marrow or both, a high incidence of cognitive impairment and P3 abnormalities were found in patients which significantly improved with vitamin B12 treatment. An abnormal Mini Mental State Examination (MMSE) score was found in 17 of the patients. Treatment with vitamin B12 was found to improve the conditions. The authors conclude, "There is high incidence of reversible cognitive impairment and P3 abnormalities in B12 deficiency neurological syndromes."

I recommend B12 shots in any one with brain dysfunction, but some doctors won't give them. The Energy Revitalization System vitamin powder and B complex will bring the B12 levels up over time (and 5,000 mcg sublingual B12 tabs can also be added). Nonetheless, if your physician is so out of date with the data that they won't even allow you the option of safe and cheap B12 shots, it's time to get a consultation with a Holistic Physician as well (who can work with your other physician to add the natural components of care—which are very helpful). To find a Holistic Physician, visit the American Board of Holistic Medicine.

References

"Vitamin B12 deficiency neurological syndromes: correlation of clinical, MRI and cognitive evoked potential," Kalita J, Misra UK, et al, J Neurol, 2008; 255(3): 353-9.


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Some information on this site is from the book From Fatigued to Fantastic! Third Edition by Jacob Teitelbaum MD, copyright 2007 by Jacob Teitelbaum MD. Used by permission of Avery Publishing, an imprint of Penguin Group (USA) Inc.


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